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Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain.Indication:Dilantin is indicated for the control of grand mal and psychomotor seizures. Dilantin will prevent or effectively decrease the incidence and severity of convulsive seizures in a high percentage of cases, with patients exhibiting little tendency to become resistant to its action. Besides its effectiveness in controlling seizures, Dilantin frequently improves the mental condition and outlook of epileptic patients and there is also increasing evidence that Dilantin is valuable in the prevention of seizures occurring during or after neurosurgery and in the treatment of certain cardiac arrythmias. Phenytoin serum level determinations may be necessary for optimal dosage adjustments (see Dosage and Administration).Dosage and Administration:Dilantin capsules (30 mg, 100 mg) are formulated with the sodium salt of phenytoin.The free acid form of phenytoin is used in Dilantin Infatabs (50 mg) and Dilantin Paediatric Suspension (30 mg/5 mL).Because there is approximately an 8% increase in drug content with the free form over that of the sodium salt, dosage adjustments and serum level monitoring may be necessary when switching from a product formulated with the free acid to a product formulated with the sodium salt and vice versa.GeneralDosage should be individualised to obtain maximum benefit. In some cases, serum blood level determinations may be necessary for optimal dosage adjustments. Serum levels between 10 and 20 ?g/mL are considered to be clinically effective. With the recommended dosage, a period of at least 7 to 10 days may be required to achieve therapeutic blood levels of Dilantin, unless therapy is initiated with a loading dose. After the initial dose has been prescribed, plasma levels should be determined and the dosage adjusted if necessary to obtain a level in the therapeutic range; 10 to 20 ?g/mL (40 to 80 ?moles/L). Because phenytoin is hydroxylated in the liver by an enzyme system which is saturable, at high plasma levels small incremental doses may increase the half-life and produce very substantial increases in serum levels, when these are in the upper range.Oral AdministrationAlthough phenytoin has a relatively long plasma half-life, thrice daily dosing may reduce the incidence of gastric irritation since lower doses can be administered with thrice daily dosing as compared with twice daily dosing. Recent studies suggest that a better correlation is achieved between plasma levels and dose by expressing the latter on a body-weight basis.AdultInitiate therapy with 4 to 5 mg/kg/day in 2 to 3 divided doses and assess plasma levels. A further upward dosage adjustment may be required to a maximum of 600 mg/day, dosage increments should be made at about 2 week intervals. Plasma phenytoin levels should be monitored should higher doses be required.An initial dose of 6 to 7 mg/kg/day would be more likely to ensure therapeutic levels however, there is a risk that such a dose may achieve levels exceeding 20 ?g/mL and increase the risk of toxicity.PaediatricInitiate therapy with 5 mg/kg/day in 2 to 3 equally divided doses not to exceed 300 mg daily. A recommended daily maintenance dosage is usually 4 to 8 mg/kg. Children over 6 years may require the minimum adult dose (300 mg/day).Paediatric dosage forms available include Dilantin Chewable Infatabs and Dilantin Paediatric Suspension.
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Further information about Dilantin Infatabs:
Manufacturer
Name : D
Product Category: Prescription Drugs
Where to purchase Dilantin Infatabs
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Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain.Indication:Dilantin is indicated for the control of grand mal and psychomotor seizures. Dilantin will prevent or effectively decrease the incidence and severity of convulsive seizures in a high percentage of cases, with patients exhibiting little tendency to become resistant to its action. Besides its effectiveness in controlling seizures, Dilantin frequently improves the mental condition and outlook of epileptic patients and there is also increasing evidence that Dilantin is valuable in the prevention of seizures occurring during or after neurosurgery and in the treatment of certain cardiac arrythmias. Phenytoin serum level determinations may be necessary for optimal dosage adjustments (see Dosage and Administration).Dosage and Administration:Dilantin capsules (30 mg, 100 mg) are formulated with the sodium salt of phenytoin.The free acid form of phenytoin is used in Dilantin Infatabs (50 mg) and Dilantin Paediatric Suspension (30 mg/5 mL).Because there is approximately an 8% increase in drug content with the free form over that of the sodium salt, dosage adjustments and serum level monitoring may be necessary when switching from a product formulated with the free acid to a product formulated with the sodium salt and vice versa.GeneralDosage should be individualised to obtain maximum benefit. In some cases, serum blood level determinations may be necessary for optimal dosage adjustments. Serum levels between 10 and 20 ?g/mL are considered to be clinically effective. With the recommended dosage, a period of at least 7 to 10 days may be required to achieve therapeutic blood levels of Dilantin, unless therapy is initiated with a loading dose. After the initial dose has been prescribed, plasma levels should be determined and the dosage adjusted if necessary to obtain a level in the therapeutic range; 10 to 20 ?g/mL (40 to 80 ?moles/L). Because phenytoin is hydroxylated in the liver by an enzyme system which is saturable, at high plasma levels small incremental doses may increase the half-life and produce very substantial increases in serum levels, when these are in the upper range.Oral AdministrationAlthough phenytoin has a relatively long plasma half-life, thrice daily dosing may reduce the incidence of gastric irritation since lower doses can be administered with thrice daily dosing as compared with twice daily dosing. Recent studies suggest that a better correlation is achieved between plasma levels and dose by expressing the latter on a body-weight basis.AdultInitiate therapy with 4 to 5 mg/kg/day in 2 to 3 divided doses and assess plasma levels. A further upward dosage adjustment may be required to a maximum of 600 mg/day, dosage increments should be made at about 2 week intervals. Plasma phenytoin levels should be monitored should higher doses be required.An initial dose of 6 to 7 mg/kg/day would be more likely to ensure therapeutic levels however, there is a risk that such a dose may achieve levels exceeding 20 ?g/mL and increase the risk of toxicity.PaediatricInitiate therapy with 5 mg/kg/day in 2 to 3 equally divided doses not to exceed 300 mg daily. A recommended daily maintenance dosage is usually 4 to 8 mg/kg. Children over 6 years may require the minimum adult dose (300 mg/day).Paediatric dosage forms available include Dilantin Chewable Infatabs and Dilantin Paediatric Suspension.
Pfizer
Dilantin Infatabs
50mg 200 Tablets
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Quality RX stock 100's of prescription drug products. They have shipping facilities for International customers. The shipping address depends on the product you have ordered and from which manufacturer or wholesaler it is being supplied from. Standard Air Mail shipments normally arrive within 10 - 28 days of being shipped. They generally ship within 24 hrs of processing the order or next business day, but delays may occur when items are on back order. If an item is on back order it can take up to 7 days to be back in stock. They are based outside the US and products are often sold under a different name. They are the same brand name product, sold by the same company under a different name or equivalent brand name product made by another pharmaceutical company. They guarantee all deliveries. If your shipment does not make its destination within 28 days, they will reship or refund at no extra cost. No questions asked. All drugs that they offer on their site are in their generic form, and listed by their brand name. Every drug in existence is given a generic name upon its creation. The most popular and mass marketed drugs are then given a copyright brand or trade name for sales purposes. This is very similar to the way actors use a stage name. Just as the actor is one person with two names, these drugs are one chemical with two names. Stage names and brand names serve the same purpose, for the public to identify and easily remember the specific drug. The drugs supplied by Quality RX are manufactured in India, home to an enormous pharmaceutical industry, largely owned and operated by US drug companies. Under international law, Indian patent law allows scientists to reverse-engineer the active molecule of brand name drugs using a different process than the original patent, thereby allowing these manufacturers to obtain a process patent of their own. These drugs, legally made and patented in India without huge development and advertising costs, can be sold legally worldwide, at a fraction of the cost of the name brand they duplicate. That is why Quality RX can offer their low prices. As a result, India has become the largest producer of generic drugs in the world, with a quality that meets all health and medical standards. Their pills and caps are factory machine sealed in bubble packaging, untouched by human hands. They accept both Visa Card and Mastercard as a form of payment. They apologise for any inconvenience caused by not offering more payment solutions.
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